Buy Plinest UK. Plinest Newest is a variation that includes hyaluronic acid (HA). In short, the HA and Mannitol enhance hydration under the skin, give better lift and boost skin radiance for patients with dry and wrinkled skin. Like all Plinest range of products, at its core, Newest promotes bio-revitalisation to reverse signs of aging. The HA and Mannitol support the regeneration triggered by the polynucleotides by adding volume and moisture.